4-Benzyloxy-phenylboronic acid → 8-(4-Benzyloxy-phenyl)-6,7-dihydro-5H-1,4,8a-triaza-s-indacene

HRID 2251116Notes

Reaction equation

HRID 2251116 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[N:16]3[C:20]([N:21]=[C:22]4CC[CH2:26][CH2:25][CH2:24][C:23]=24)=[CH:19][CH:18]=[N:17]3)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.ClC1N2C(=CC=N2)N=C2C=1CCC2.C(OC1C=CC(B(O)O)=CC=1)C1C=CC=CC=1>>[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([C:15]2[N:16]3[C:20](=[CH:19][CH:18]=[N:17]3)[N:21]=[C:22]3[C:23]=2[CH2:24][CH2:25][CH2:26]3)=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 27343144-Benzyloxy-phenylboronic acidHCID 5858771710-(4-benzyloxy-phenyl)-6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]indeneHCID 638208088-Chloro-6,7-dihydro-5H-1,4,8a-triaza-s-indacene

Product 1

HCID 692552828-(4-Benzyloxy-phenyl)-6,7-dihydro-5H-1,4,8a-triaza-s-indacene

Procedure

Using the method described for the preparation of 10-(4-benzyloxy-phenyl)-6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]indene, the reaction of 8-chloro-6,7-dihydro-5H-1,4,8a-triaza-s indacene and 4-benzyloxyphenyl boronic acid provided the title compound.

Sources & evidence

ORD record
ord-35fadcee45774c7bad1d92219ae0a454
Source dataset
uspto-grants-2008_01
Patent number
US07319103B2

Reaction notes

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