Pyrazol-3-ylamine → HCID 178515164, compound

HRID 2251131Notes

Reaction equation

HRID 2251131 reaction equation
[N:1]1[N:9]2[C:4]([N:5]=[C:6]3[CH2:15]CCC[CH2:11][C:7]3=[C:8]2[OH:10])=[CH:3][CH:2]=1.C[O:17]C(C1C(=O)COC1)=O.N1NC(N)=CC=1>C(O)(=O)C>[N:1]1[N:9]2[C:4]([N:5]=[C:6]3[C:7](=[C:8]2[OH:10])[CH2:11][O:17][CH2:15]3)=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 74561Pyrazol-3-ylamineHCID 14666564Methyl 4-oxooxolane-3-carboxylateHCID 178515163HCID 178515163, compound

Product 1

HCID 178515164HCID 178515164, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Using the method described for the preparation of 6,7,8,9-Tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]inden-10-ol, the reaction of 4-oxo-tetrahydro-furan-3-carboxylic acid methyl ester and 2H-pyrazol-3-ylamine in acetic acid provided the desired 5H,7H-6-Oxa-1,4,8a-triaza-s-indacen-8-ol.

Sources & evidence

ORD record
ord-d8f6a8baed314ad0a3a2e697f4692379
Source dataset
uspto-grants-2008_01
Patent number
US07319103B2

Reaction notes

Loading…