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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251197Generated: November 1, 2026

Hydrochloric Acid → 1-(4-Oxazol-2-yl-phenyl)-piperazine hydrochloride

https://huagongshe.com/reaction/2251197

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant4-(4-Oxazol-2-yl-phenyl)-piperazine-1-carboxylic acid tert-butyl esterHCID 69042106—
Solvent1,4-DioxaneHCID 31275—
Product1-(4-Oxazol-2-yl-phenyl)-piperazine hydrochlorideHCID 69042406—

Reaction Steps

Prepared in analogy to example 4.4 (b) from 4-(4-Oxazol-2-yl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester and hydrochloric acid in dioxane. MS (m/e): 230.1 (MH+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319099B2
Source datasetuspto-grants-2008_01
ORD IDord-8e2f4c98115746519da7b20f6f16aaec
Source noteuspto-grants-2008_01