4-Bromobenzohydrazide → 2-(4-Bromophenyl)-1,3,4-oxadiazole

Participants

Role	Name	HCID	Charge
Reactant	4-Bromobenzohydrazide	HCID 22219	—
Reactant	Ethyl orthoformate	HCID 31214	—
Product	2-(4-Bromophenyl)-1,3,4-oxadiazole	HCID 715120	—

Reaction Steps

12.3 mmol of 4-bromo-benzoic acid hydrazide were dissolved in 26 ml of triethyl orthoformate. The reaction mixture was stirred overnight at 140°, evaporated and the residue crystallized from ethanol to give the title compound as a colorless solid. MS (m/e): 225.0 (MH+, 100%)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07319099B2
Source dataset	uspto-grants-2008_01
ORD ID	ord-6f7ed09378e946969957e21323d826d2
Source note	uspto-grants-2008_01