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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251200Generated: October 26, 2026

Hydrochloric Acid → 1-[4-(5-Methyl-[1,3,4]oxadiazol-2-yl)-phenyl]-piperazine hydrochloride

https://huagongshe.com/reaction/2251200

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
Reactant4-(4-[1,3,4]Oxadiazol-2-yl-phenyl)-piperazine-1-carboxylic acid tert-butyl esterHCID 69037584—
Product1-[4-(5-Methyl-[1,3,4]oxadiazol-2-yl)-phenyl]-piperazine hydrochlorideHCID 69037877—

Reaction Steps

Prepared in analogy to example 4.4 (b) from 4-(4-[1,3,4]Oxadiazol-2-yl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester and hydrochloric acid in dioxane. MS (m/e): 245.3 (MH+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319099B2
Source datasetuspto-grants-2008_01
ORD IDord-1a3c4a216626426192475478d2582d1f
Source noteuspto-grants-2008_01