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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251214Generated: November 4, 2026

Trifluoroacetic acid → 2-Methoxy-6-(piperazin-1-yl)pyrazine

https://huagongshe.com/reaction/2251214

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant6'-Methoxy-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-carboxylic acid tert-butyl esterHCID 69041341—
Product2-Methoxy-6-(piperazin-1-yl)pyrazineHCID 13318698—

Reaction Steps

Prepared in analogy to example 4.10 (c) from 6′-Methoxy-2,3,5,6-tetrahydro-[1,2′]bipyrazinyl-4-carboxylic acid tert-butyl ester and trifluoroacetic acid. MS (m/e): 195.1 (MH+, 80%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319099B2
Source datasetuspto-grants-2008_01
ORD IDord-ddeed2bd50a942b9afded2d572acd744
Source noteuspto-grants-2008_01