2-Dimethylcarbamoyloxy-5-methanesulfonyl-benzoic acid benzyl ester → 2-Dimethylcarbamoyloxy-5-methanesulfonyl-benzoic acid

HRID 2251219Notes

Reaction equation

HRID 2251219 reaction equation
C([O:8][C:9](=[O:26])[C:10]1[CH:15]=[C:14]([S:16]([CH3:19])(=[O:18])=[O:17])[CH:13]=[CH:12][C:11]=1[O:20][C:21](=[O:25])[N:22]([CH3:24])[CH3:23])C1C=CC=CC=1>CO.[Pd]>[CH3:23][N:22]([CH3:24])[C:21]([O:20][C:11]1[CH:12]=[CH:13][C:14]([S:16]([CH3:19])(=[O:18])=[O:17])=[CH:15][C:10]=1[C:9]([OH:26])=[O:8])=[O:25]

Participants

4

Reactant 1

HCID 690360752-Dimethylcarbamoyloxy-5-methanesulfonyl-benzoic acid benzyl ester

Product 1

HCID 690391012-Dimethylcarbamoyloxy-5-methanesulfonyl-benzoic acid

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

1 mmol of 2-dimethylcarbamoyloxy-5-methanesulfonyl-benzoic acid benzyl ester was dissolved in 5 ml of methanol. 25 mg of palladium 10% on charcoal was added and the reaction mixture hydrogenated at room temperature to yield the title compound as a slightly yellowish solid. MS (m/e): 288.0 (MH+, 66%)

Sources & evidence

ORD record
ord-d71bf0c8caa547c88ac500096c3e2542
Source dataset
uspto-grants-2008_01
Patent number
US07319099B2

Reaction notes

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