Ethanol → 1,3-Dioxol-2-one, 4-(4-methylphenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-, monohydrochloride

HRID 225124Notes

Reaction equation

HRID 225124 reaction equation
Cl.F[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][C:11](=[O:30])[O:12][C:13]=2[CH2:14][CH2:15][N:16]2[CH2:21][CH2:20][N:19]([C:22]3[CH:27]=[C:26]([Cl:28])[CH:25]=[C:24](Cl)[CH:23]=3)[CH2:18][CH2:17]2)=[CH:5][CH:4]=1.[CH2:31](O)C>>[ClH:28].[C:3]1([CH3:31])[CH:8]=[CH:7][C:6]([C:9]2[O:10][C:11](=[O:30])[O:12][C:13]=2[CH2:14][CH2:15][N:16]2[CH2:21][CH2:20][N:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH2:18][CH2:17]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 702EthanolHCID 30550124-{2-[4-(3,5-Dichlorophenyl)piperazin-1-yl]ethyl}-5-(4-fluorophenyl)-2H-1,3-dioxol-2-one--hydrogen chloride (1/1)

Product 1

HCID 30550101,3-Dioxol-2-one, 4-(4-methylphenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-, monohydrochloride

Procedure

4-(4-fluorophenyl)-5-[2-(4-(3,5-dichlorophenyl)-1-piperazinyl)ethyl]-1,3-dioxol-2-one hydrochloride m.p.=277°-9° C. (from ethanol

Sources & evidence

ORD record
ord-e0866fb569c14e65a0d674c30dfdeab3
Source dataset
uspto-grants-1980_11
Patent number
US04235904

Reaction notes

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