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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251285Generated: October 25, 2026

Bromocyclopropane → (2-Allyloxy-5-nitro-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

https://huagongshe.com/reaction/2251285

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromocyclopropaneHCID 78037—
Reactant(2-Hydroxy-5-nitro-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanoneHCID 69036826—
Product(2-Allyloxy-5-nitro-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanoneHCID 69036586—

Reaction Steps

The title compound was prepared in analogy to example 62 from (2-Hydroxy-5-nitro-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound 2.1) and cyclopropyl bromide. MS (m/e): 436.5 (MH+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319099B2
Source datasetuspto-grants-2008_01
ORD IDord-fe394a313e8649789e51a43a6f739bb6
Source noteuspto-grants-2008_01