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1-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazine → (2-Benzyloxy-5-methanesulfonyl-phenyl)-[4-(3-fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazine | HCID 44184874 | — |
| 反応物 | 2-Benzyloxy-5-methanesulfonyl-benzoic acid | HCID 68826683 | — |
| 生成物 | (2-Benzyloxy-5-methanesulfonyl-phenyl)-[4-(3-fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-methanone | HCID 69042385 | — |
反応手順
The title compound was prepared in analogy to example 5 from 1-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazine (compound 5.5) and 2-Benzyloxy-5-methanesulfonyl-benzoic acid (compound 7.5). MS (m/e): 538.4 (MH+, 100%)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07319099B2 |
| 出典データセット | uspto-grants-2008_01 |
| ORD ID | ord-f235a977b5bf49fa81148850ec106ec6 |
| 出典メモ | uspto-grants-2008_01 |