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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251288Generated: October 25, 2026

1-[2-Fluoro-4-(methylsulfonyl)phenyl]piperazine → (2-Benzyloxy-5-methanesulfonyl-phenyl)-[4-(2-fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-methanone

https://huagongshe.com/reaction/2251288

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-Fluoro-4-(methylsulfonyl)phenyl]piperazineHCID 2782730—
Reactant2-Benzyloxy-5-methanesulfonyl-benzoic acidHCID 68826683—
Product(2-Benzyloxy-5-methanesulfonyl-phenyl)-[4-(2-fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-methanoneHCID 69037318—

Reaction Steps

The title compound was prepared in analogy to example 5 from 1-(2-Fluoro-4-methanesulfonyl-phenyl)-piperazine (commercial) and 2-Benzyloxy-5-methanesulfonyl-benzoic acid (compound 7.5). MS (m/e): 547.4 (MH+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319099B2
Source datasetuspto-grants-2008_01
ORD IDord-ebc19c3a0961402cb46f7b2fe192002e
Source noteuspto-grants-2008_01