3-Methoxybenzenesulfonyl chloride → HCID 10206696, compound

HRID 2251376Notes

Reaction equation

HRID 2251376 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:14][CH2:13][CH2:12][N:11](C(OC(C)(C)C)=O)[CH2:10][CH2:9]2)=[CH:4][C:3]=1[NH:22][S:23]([CH3:26])(=[O:25])=[O:24].[CH3:27][O:28][C:29]1[CH:30]=[C:31]([S:35]([Cl:38])(=[O:37])=[O:36])[CH:32]=[CH:33][CH:34]=1>>[ClH:38].[N:8]1([C:5]2[CH:6]=[CH:7][C:2]([NH:1][S:35]([C:31]3[CH:32]=[CH:33][CH:34]=[C:29]([O:28][CH3:27])[CH:30]=3)(=[O:37])=[O:36])=[C:3]([NH:22][S:23]([CH3:26])(=[O:24])=[O:25])[CH:4]=2)[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 27375043-Methoxybenzenesulfonyl chlorideHCID 22272520HCID 22272520, compound

Product 1

HCID 10206696HCID 10206696, compound

Procedure

The compound was synthesized from N-{2-amino-5-(4-t-butyloxycarbonyl-1,4-diazepan-1-yl)- phenyl}methanesulfonamide and 3-methoxybenzenesulfonylchloride (94 mg, 0.455 mmol) to give 160 mg as a purple solid. M+1 455.2 Calcd 455.13.

Workup

  1. customto give 160 mg as a purple solid

Sources & evidence

ORD record
ord-eb403c67ecaf4079a22a1fd1b10e7ea9
Source dataset
uspto-grants-2008_01
Patent number
US07319097B2

Reaction notes

Loading…