tert-Butyl 2-bromopropanoate → HCID 59643215, compound

HRID 2251484Notes

Reaction equation

HRID 2251484 reaction equation
[CH2:1]([C:3]1[CH:4]=[N:5][C:6]([N:9]([CH2:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:22][CH:21]=2)[CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)=[N:7][CH:8]=1)[CH3:2].Br[CH:31]([CH3:39])[C:32]([O:34]C(C)(C)C)=[O:33]>>[CH2:1]([C:3]1[CH:8]=[N:7][C:6]([N:9]([CH2:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:28])([F:29])[F:27])=[CH:22][CH:21]=2)[CH2:10][CH2:11][C:12]2[CH:13]=[CH:14][C:15]([O:18][CH:31]([CH3:39])[C:32]([OH:34])=[O:33])=[CH:16][CH:17]=2)=[N:5][CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 545327tert-Butyl 2-bromopropanoateHCID 59643341HCID 59643341, compound

Product 1

HCID 59643215HCID 59643215, compound

Procedure

Similarly prepared from 4-(2-{(5-ethylpyrimidin-2-yl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenol and t-butyl 2-bromopropionate.

Sources & evidence

ORD record
ord-f270c3723c0b4c29932a00e59847db28
Source dataset
uspto-grants-2008_01
Patent number
US07319104B2

Reaction notes

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