HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 59643198, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-Chloro-5-ethylpyrimidine | HCID 3572763 | — |
| Reactant | HCID 69099560 | HCID 69099560 | — |
| Product | HCID 59643198 | HCID 59643198 | 76.2% |
Reaction Steps
Condensation of 4-(2-{[4-(trifluoromethoxy)benzyl]amino}ethyl)phenol (500 mg; 1.61 mmol) with 2-chloro-5-ethyl-pyrimidine (0.19 ml; 1.54 mmol) as per general procedure E (conditions: 5 ml of DIEA, 200C, 16 hr) provided the title compound (490 mg; 76% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07319104B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-d16178b0bbc6431e9eaf8acdd4ecdda6 |
| Source note | uspto-grants-2008_01 |