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HRID225149

反应详情

EQUATION

反应方程式

HRID 225149 的结构方程式

REACTANTS

反应物

4
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：O=C(CBr)C1COc2ccccc2O1
HCID12608585

2-Bromo-1-(2,3-dihydro-1,4-benzodioxin-2-yl)ethan-1-one

C10H9BrO3

结构：O=C(Nc1cccs1)NC1CCNCC1
HCID23329071

1-(Piperid-4-yl)-3-(2-thienyl)urea

C10H15N3OS

结构：O=C(Nc1cccs1)NC1CCN(CC(=O)C2COc3ccccc3O2)CC1
HCID23329075

1-[2-Thienyl]-3-[1-(2-[1,4-benzodioxan-2-yl]-2-oxoethyl)piperid-4-yl]urea

C20H23N3O4S

PRODUCTS

生成物

1
结构：O=C(Nc1cccs1)NC1CCN(CC(O)C2COc3ccccc3O2)CC1
HCID23329077

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Na+].[OH-]
溶剂HCID14798

Sodium Hydroxide

HNaO

结构：CCN(CC)CC.CN(C)C=O
溶剂HCID22056947

triethylamine N,N-dimethylformamide

C9H22N2O

PROCEDURE

实验过程

1-[2-Thienyl]-3-[1-(2-[1,4-benzodioxan-2-yl]-2-oxoethyl)piperid-4-yl]urea, prepared by reacting 1-(piperid-4-yl)-3-(2-thienyl)urea with 2-bromoacetyl-1,4-benzodioxan in DMF/Et3N, may be reduced using sodium borohydride in 2 N sodium hydroxide to give the title compound.