2-(3-Bromo-4-methoxyphenyl)ethan-1-amine → N-[2-(3-bromo-4-methoxyphenyl)ethyl]-5-isopropylpyrimidin-2-amine

HRID 2251495Notes

Reaction equation

HRID 2251495 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH2:10][CH2:11][NH2:12])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].Cl[C:14]1[N:19]=[CH:18][C:17]([CH:20]([CH3:22])[CH3:21])=[CH:16][N:15]=1>>[Br:1][C:2]1[CH:3]=[C:4]([CH2:10][CH2:11][NH:12][C:14]2[N:19]=[CH:18][C:17]([CH:20]([CH3:22])[CH3:21])=[CH:16][N:15]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9]

Participants

3

Reactant 2

HCID 27355812-(3-Bromo-4-methoxyphenyl)ethan-1-amineHCID 198466722-Chloro-5-isopropylpyrimidine

Product 1

HCID 59643254N-[2-(3-bromo-4-methoxyphenyl)ethyl]-5-isopropylpyrimidin-2-amine

Procedure

Similarly prepared from 2-(3-bromo-4-methoxyphenyl)ethanamine and 2-chloro-5-isopropyl-pyrimidine (see below).

Sources & evidence

ORD record
ord-0f05021c068c4a9484ec59de092b29b4
Source dataset
uspto-grants-2008_01
Patent number
US07319104B2

Reaction notes

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