1-(Bromomethyl)-4-ethylbenzene → 4-{2-[(4-Ethylbenzyl)(5-ethylpyrimidin-2-yl)amino]ethyl}-2-methylphenol

HRID 2251501노트

반응식

HRID 2251501 반응식
[CH2:1]([C:3]1[CH:4]=[N:5][C:6]([NH:9][CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][C:15]([O:18]C)=[C:14]([CH3:20])[CH:13]=2)=[N:7][CH:8]=1)[CH3:2].[CH2:21]([C:23]1[CH:30]=[CH:29][C:26]([CH2:27]Br)=[CH:25][CH:24]=1)[CH3:22]>>[CH2:21]([C:23]1[CH:30]=[CH:29][C:26]([CH2:27][N:9]([C:6]2[N:5]=[CH:4][C:3]([CH2:1][CH3:2])=[CH:8][N:7]=2)[CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[C:14]([CH3:20])[CH:13]=2)=[CH:25][CH:24]=1)[CH3:22]

참가 물질

3

반응물 2

HCID 122315601-(Bromomethyl)-4-ethylbenzeneHCID 596433985-ethyl-N-[2-(4-methoxy-3-methylphenyl)ethyl]pyrimidin-2-amine

생성물 1

HCID 596433944-{2-[(4-Ethylbenzyl)(5-ethylpyrimidin-2-yl)amino]ethyl}-2-methylphenol

실험 절차

Similarly prepared from 5-ethyl-N-[2-(4-methoxy-3-methylphenyl)ethyl]pyrimidin-2-amine and 4-ethyl-benzyl bromide.

출처 및 근거

ORD 기록
ord-96db6b87f8734d6ab07c4d7e5cb03e06
출처 데이터셋
uspto-grants-2008_01
특허 번호
US07319104B2

반응 노트

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