1-(Bromomethyl)-3-(trifluoromethoxy)benzene → HCID 59643250, compound

HRID 2251504Notes

Reaction equation

HRID 2251504 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:10][CH2:11][NH:12][C:13]2[N:18]=[CH:17][C:16]([CH2:19][CH3:20])=[CH:15][N:14]=2)[CH:5]=[CH:6][C:7]=1[O:8]C.[F:21][C:22]([F:33])([F:32])[O:23][C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=1)[CH2:27]Br>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:10][CH2:11][N:12]([C:13]2[N:18]=[CH:17][C:16]([CH2:19][CH3:20])=[CH:15][N:14]=2)[CH2:27][C:26]2[CH:29]=[CH:30][CH:31]=[C:24]([O:23][C:22]([F:21])([F:32])[F:33])[CH:25]=2)[CH:5]=[CH:6][C:7]=1[OH:8]

Participants

3

Reactant 2

HCID 7371761-(Bromomethyl)-3-(trifluoromethoxy)benzeneHCID 59643263HCID 59643263, compound

Product 1

HCID 59643250HCID 59643250, compound

Procedure

Similarly prepared from N-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-ethylpyrimidin-2-amine and 3-trifluoromethoxy benzyl bromide.

Sources & evidence

ORD record
ord-3776809ddb2343c7bc097b6954425b09
Source dataset
uspto-grants-2008_01
Patent number
US07319104B2

Reaction notes

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