1-(Bromomethyl)-3-(trifluoromethoxy)benzene → HCID 59643258, compound

HRID 2251513Notes

Reaction equation

HRID 2251513 reaction equation
[CH2:1]([C:3]1[CH:4]=[N:5][C:6]([NH:9][CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][C:15]([O:18]C)=[C:14]([CH3:20])[C:13]=2[CH3:21])=[N:7][CH:8]=1)[CH3:2].[F:22][C:23]([F:34])([F:33])[O:24][C:25]1[CH:26]=[C:27]([CH:30]=[CH:31][CH:32]=1)[CH2:28]Br>>[CH2:1]([C:3]1[CH:4]=[N:5][C:6]([N:9]([CH2:28][C:27]2[CH:30]=[CH:31][CH:32]=[C:25]([O:24][C:23]([F:22])([F:33])[F:34])[CH:26]=2)[CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[C:14]([CH3:20])[C:13]=2[CH3:21])=[N:7][CH:8]=1)[CH3:2]

Participants

3

Reactant 2

HCID 7371761-(Bromomethyl)-3-(trifluoromethoxy)benzeneHCID 59643352HCID 59643352, compound

Product 1

HCID 59643258HCID 59643258, compound

Procedure

Similarly prepared from 5-ethyl-N-[2-(4-methoxy-2,3-dimethylphenyl)ethyl]pyrimidin-2-amine and 3-trifluoromethoxy benzyl bromide.

Sources & evidence

ORD record
ord-530d0224dff245719934ea32673206d5
Source dataset
uspto-grants-2008_01
Patent number
US07319104B2

Reaction notes

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