1-(Bromomethyl)-3-(trifluoromethoxy)benzene → HCID 59643325, compound

HRID 2251514Notes

Reaction equation

HRID 2251514 reaction equation
[CH2:1]([C:3]1[CH:4]=[N:5][C:6]([NH:9][CH2:10][CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][C:16]([O:19]C)=[CH:15][CH:14]=2)=[N:7][CH:8]=1)[CH3:2].[F:21][C:22]([F:33])([F:32])[O:23][C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=1)[CH2:27]Br>>[CH2:1]([C:3]1[CH:8]=[N:7][C:6]([N:9]([CH2:27][C:26]2[CH:29]=[CH:30][CH:31]=[C:24]([O:23][C:22]([F:21])([F:32])[F:33])[CH:25]=2)[CH2:10][CH2:11][CH2:12][C:13]2[CH:14]=[CH:15][C:16]([OH:19])=[CH:17][CH:18]=2)=[N:5][CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 7371761-(Bromomethyl)-3-(trifluoromethoxy)benzeneHCID 59643419HCID 59643419, compound

Product 1

HCID 59643325HCID 59643325, compound

Procedure

Similarly prepared from 5-ethyl-N-[3-(4-methoxyphenyl)propyl]pyrimidin-2-amine and 3-trifluoromethoxy benzyl bromide.

Sources & evidence

ORD record
ord-0409c7daa11d4a5287e22907212050b0
Source dataset
uspto-grants-2008_01
Patent number
US07319104B2

Reaction notes

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