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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251549Generated: October 26, 2026

Trifluoroacetic acid → [3-(3-{(5-Isopropylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}propyl)phenoxy]acetic acid

https://huagongshe.com/reaction/2251549

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactanttert-Butyl bromoacetateHCID 79177—
Reactant3-(3-{(5-Isopropylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}propyl)phenolHCID 59643168—
Product[3-(3-{(5-Isopropylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}propyl)phenoxy]acetic acidHCID 59643342—

Reaction Steps

Similarly prepared by alkylation of 3-(3-{(5-isopropylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}propyl)phenol with tert-butyl-bromo-acetate followed by standard TFA hydrolysis.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319104B2
Source datasetuspto-grants-2008_01
ORD IDord-d2b1eb4f35034ed5bf123c8352f1328d
Source noteuspto-grants-2008_01