Chloropyrazine → HCID 59643278, compound

HRID 2251551Notes

Reaction equation

[CH3:1][C:2]([O:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][NH:18][CH2:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:22][CH:21]=2)=[CH:12][CH:11]=1)([CH3:8])[C:3]([O:5]CC)=[O:4].Cl[C:31]1[CH:36]=[N:35][CH:34]=[CH:33][N:32]=1>>[CH3:1][C:2]([O:9][C:10]1[CH:11]=[CH:12][C:13]([CH2:16][CH2:17][N:18]([C:31]2[CH:36]=[N:35][CH:34]=[CH:33][N:32]=2)[CH2:19][C:20]2[CH:21]=[CH:22][C:23]([C:26]([F:29])([F:27])[F:28])=[CH:24][CH:25]=2)=[CH:14][CH:15]=1)([CH3:8])[C:3]([OH:5])=[O:4]

Participants

Reactant 2

HCID 73277Chloropyrazine

HCID 59643115HCID 59643115, compound

Product 1

HCID 59643278HCID 59643278, compound

Procedure

Similarly prepared from ethyl 2-methyl-2-[4-(2-{[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]propanoate and chloropyrazine.

Sources & evidence

ORD record: ord-095d4ab4be2c4e85b9baa7244357f167
Source dataset: uspto-grants-2008_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07319104B2

Reaction notes

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