Water → HCID 69099586, compound

Participants

Reaction Steps

To a solution of bromobenzoic acid (9.97 g, 49.60 mmol) in DMF (65 mL) was added Na2CO3 (7.90 g, 74.54 mmol). After stirring for 15 min, 2-bromo-1-cyclopropylethanone (9.69 g, 59.44 mmol) was added, and the mixture was stirred at rt for 12 h. Water was added, and the mixture was extracted with Et2O (6×125 ml). The combined organic phases were dried with MgSO4 and concentrated in vacuo. Recrystallization from EtOH yielded 2-cyclopropyl-2-oxoethyl 4-bromobenzoate as white needles (8.53 g, 61%).

Provenance & Evidence