Cyclohexanecarbonyl chloride → HCID 59643410, compound

HRID 2251578Notes

Reaction equation

[NH2:1]/[C:2](/[N:5]([CH2:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]([F:35])([F:34])[F:33])=[CH:28][CH:27]=1)[CH2:6][CH2:7][C:8]1[CH:24]=[CH:23][C:11]([O:12][C:13]([CH3:22])([CH3:21])[C:14]([O:16]C(C)(C)C)=[O:15])=[CH:10][CH:9]=1)=[N:3]\[OH:4].[CH:36]1([C:42](Cl)=O)[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]1>>[CH:36]1([C:42]2[O:4][N:3]=[C:2]([N:5]([CH2:25][C:26]3[CH:31]=[CH:30][C:29]([C:32]([F:33])([F:35])[F:34])=[CH:28][CH:27]=3)[CH2:6][CH2:7][C:8]3[CH:24]=[CH:23][C:11]([O:12][C:13]([CH3:21])([CH3:22])[C:14]([OH:16])=[O:15])=[CH:10][CH:9]=3)[N:1]=2)[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]1

Participants

Reactant 2

HCID 75938Cyclohexanecarbonyl chloride

HCID 59643363HCID 59643363, compound

Product 1

HCID 59643410HCID 59643410, compound

Procedure

Similarly prepared from tert-butyl 2-[4-(2-{[(E)-amino(hydroxyimino)methyl][4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and cyclohexanecarbonyl chloride.

Sources & evidence

ORD record: ord-c1b68cb49838413e81f2e546c8a34dfe
Source dataset: uspto-grants-2008_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07319104B2

Reaction notes

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