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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251580Generated: October 25, 2026

3-Bromo-1,1,1-trifluoro-2-propanone → 2-Methyl-2-[4-(2-{[4-(trifluoromethyl)benzyl][4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}ethyl)phenoxy]propanoic acid

https://huagongshe.com/reaction/2251580

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-1,1,1-trifluoro-2-propanoneHCID 79008—
ReactantEthyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoateHCID 59643246—
Product2-Methyl-2-[4-(2-{[4-(trifluoromethyl)benzyl][4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}ethyl)phenoxy]propanoic acidHCID 59643243—

Reaction Steps

Similarly prepared from ethyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and 3-bromo-1,1,1-trifluoroacetone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319104B2
Source datasetuspto-grants-2008_01
ORD IDord-968453f06f764f3b9749763e72f5f6dc
Source noteuspto-grants-2008_01