Bromomethyl 3-methoxyphenyl ketone → 2-[4-(2-{[4-(3-Methoxyphenyl)-1,3-thiazol-2-yl][4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoic acid

Participants

Role	Name	HCID	Charge
Reactant	Bromomethyl 3-methoxyphenyl ketone	HCID 101294	—
Reactant	Ethyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate	HCID 59643246	—
Product	2-[4-(2-{[4-(3-Methoxyphenyl)-1,3-thiazol-2-yl][4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoic acid	HCID 59643289	—

Reaction Steps

Similarly prepared from ethyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and 3-methoxyphenacyl bromide.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07319104B2
Source dataset	uspto-grants-2008_01
ORD ID	ord-59a3bcdf3b304a28a21b71652f189f76
Source note	uspto-grants-2008_01