3-Bromo-1,1,1-trifluoro-2-propanone → 2-[4-(2-{[2,4-Bis(trifluoromethyl)benzyl][4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}ethyl)phenoxy]-2-methylpropanoic acid

Participants

Role	Name	HCID	Charge
Reactant	3-Bromo-1,1,1-trifluoro-2-propanone	HCID 79008	—
Reactant	Ethyl 2-[4-(2-{(aminocarbonothioyl)[2,4-bis(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate	HCID 59643200	—
Product	2-[4-(2-{[2,4-Bis(trifluoromethyl)benzyl][4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}ethyl)phenoxy]-2-methylpropanoic acid	HCID 59643433	—

Reaction Steps

Similarly prepared from ethyl 2-[4-(2-{(aminocarbonothioyl)[2,4-bis(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and 3-bromo-1,1,1-trifluoroacetone.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07319104B2
Source dataset	uspto-grants-2008_01
ORD ID	ord-03342c05b6814913878a67e4e8d21ec0
Source note	uspto-grants-2008_01