HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(4-fluorophenyl)ethan-1-one → 2-[4-(2-{[2,4-Bis(trifluoromethyl)benzyl][4-(4-fluorophenyl)-1,3-thiazol-2-yl]amino}ethyl)phenoxy]-2-methylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(4-fluorophenyl)ethan-1-one | HCID 96749 | — |
| Reactant | Ethyl 2-[4-(2-{(aminocarbonothioyl)[2,4-bis(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate | HCID 59643200 | — |
| Product | 2-[4-(2-{[2,4-Bis(trifluoromethyl)benzyl][4-(4-fluorophenyl)-1,3-thiazol-2-yl]amino}ethyl)phenoxy]-2-methylpropanoic acid | HCID 59643268 | — |
Reaction Steps
Similarly prepared from ethyl 2-[4-(2-{(aminocarbonothioyl)[2,4-bis(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and 4-fluorophenacyl bromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07319104B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-96e72e58091447eebf01ea6742ea79a1 |
| Source note | uspto-grants-2008_01 |