Potassium Carbonate → Methyl 2,2-diphenyl-6-thiazol-2-yl-1,3-benzodioxole-4-carboxylate

Participants

Reaction Steps

Methyl 6-bromo-2,2-diphenyl-1,3-benzodioxole-4-carboxylate (250 mg, 0.608 mmol, 1 eq.) Pd(PPh3)4 (70 mg, 0.06 mmol, 0.1 eq.), bis(pinacolato)diboron (200 mg, 0.79 mmol, 1.3 eq.) and KOAc (90 mg, 0.912 mmol, 1.5 eq.), then Pd(PPh3)4 (70 mg, 0.06 mmol, 0.1 eq.), 2-bromo-thiazole (110 mg, 0.67 mmol, 1.1 eq.) and K2CO3 (420 mg, 3.04 mmol, 5 eq.) were used according to GP6 to yield the title product as a colorless solid.

Provenance & Evidence