Potassium Carbonate → HCID 59643005, compound

Participants

Role	Name	HCID	Charge
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	Potassium Acetate	HCID 517044	—
Reactant	Bis(pinacolato)diborane	HCID 2733548	—
Reactant	Methyl 6-bromo-2,2-diphenyl-1,3-benzodioxole-4-carboxylate	HCID 59642990	—
Reactant	2-Bromopyridine--hydrogen chloride (1/1)	HCID 71370504	—
Catalyst	HCID 178418397	HCID 178418397	—
Product	HCID 59643005	HCID 59643005	—

Reaction Steps

Methyl 6-bromo-2,2-diphenyl-1,3-benzodioxole-4-carboxylate (400 mg, 0.973 mmol, 1 eq.), Pd(PPh3)4 (100 mg, 0.087 mmol, 0.09 eq.), bis(pinacolato)diboron (320 mg, 1.26 mmol, 1.3 eq.) and KOAc (150 mg, 1.5 mmol, 1.5 eq.), then Pd(PPh3)4 (112 mg, 0.097 mmol, 0.1 eq.), 2-bromo-pyridine hydrochloride (265 mg, 1.36 mmol, 1.4 eq.) and K2CO3 (680 mg, 4.9 mmol, 5 eq.) were used according to GP6 to yield the title product as a colorless solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07319101B2
Source dataset	uspto-grants-2008_01
ORD ID	ord-ede8888fa88a430790cb1ddd4ce593eb
Source note	uspto-grants-2008_01