Ethanol → HCID 23329105, compound

HRID 225163Notes

Reaction equation

HRID 225163 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:14])[CH2:9][CH2:10][C:11]([OH:13])=[O:12])=[CH:4][C:3]=1[S:15](=[O:19])(=[O:18])[NH:16][CH3:17].[C:20](Cl)(=O)C.C(O)C>CO>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:14])[CH2:9][CH2:10][C:11]([O:13][CH3:20])=[O:12])=[CH:4][C:3]=1[S:15](=[O:19])(=[O:18])[NH:16][CH3:17]

Participants

5

Reactant 3

HCID 702EthanolHCID 6367Acetyl chlorideHCID 23329149HCID 23329149, compound

Product 1

HCID 23329105HCID 23329105, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 12 g of 4-(4-chloro-3-methylsulfamoylphenyl)-4-oxobutanoic acid and 1.2 g of acetyl chloride in 120 ml of methanol is reacted for 48 hours and worked up, analogously to the instructions indicated in Example 2(a). Methyl 4-(4-chloro-3-methylsulfamoylphenyl)-4-oxobutanoate of melting point 112°-114° C. (from ethanol) is obtained.

Workup

  1. customis reacted for 48 hours

Sources & evidence

ORD record
ord-a7b0ba35c3c245b2b136e41cfd3a302f
Source dataset
uspto-grants-1980_11
Patent number
US04235918

Reaction notes

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