1-Methylpyrrole-2-carbonitrile → HCID 16004661, compound

HRID 2251641Notes

Reaction equation

HRID 2251641 reaction equation
[CH3:1][C:2]1([CH3:20])[C:10]2[C:5](=[CH:6][CH:7]=[C:8](OS(C(F)(F)F)(=O)=O)[CH:9]=2)[C:4](=[O:19])[CH2:3]1.[CH3:21][N:22]1[CH:26]=[CH:25][CH:24]=[C:23]1[C:27]#[N:28]>>[CH3:1][C:2]1([CH3:20])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:26]3[N:22]([CH3:21])[C:23]([C:27]#[N:28])=[CH:24][CH:25]=3)[CH:9]=2)[C:4](=[O:19])[CH2:3]1

Participants

3

Reactant 2

HCID 20641111-Methylpyrrole-2-carbonitrileHCID 57618520Trifluoromethanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester

Product 1

HCID 16004661HCID 16004661, compound

Procedure

The title compound was prepared from trifluoro-methanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester and 1-methyl-2-cyanopyrrole according to the same coupling procedure as described in example 1. MS (ES) m/z 265.1. HRMS: calcd for C17H16N2O+H+, 265.13354; found (ESI, [M+H]+), 265.1332.

Sources & evidence

ORD record
ord-ccd58638b88d4d81b8e82c87091a14bf
Source dataset
uspto-grants-2008_01
Patent number
US07319152B2

Reaction notes

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