1-Methylpyrrole-2-carbonitrile → HCID 16225747, compound

HRID 2251653Notes

Reaction equation

HRID 2251653 reaction equation
[O:1]=[C:2]1[CH2:11][CH2:10][CH2:9][C:8]2[CH:7]=[C:6](OS(C(F)(F)F)(=O)=O)[CH:5]=[CH:4][C:3]1=2.[CH3:20][N:21]1[CH:25]=[CH:24][CH:23]=[C:22]1[C:26]#[N:27]>>[CH3:20][N:21]1[C:25]([C:6]2[CH:5]=[CH:4][C:3]3[C:2](=[O:1])[CH2:11][CH2:10][CH2:9][C:8]=3[CH:7]=2)=[CH:24][CH:23]=[C:22]1[C:26]#[N:27]

Participants

3

Reactant 2

HCID 20641111-Methylpyrrole-2-carbonitrileHCID 110983845-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate

Product 1

HCID 16225747HCID 16225747, compound

Procedure

The title compound was prepared from trifluoro-methanesulfonic acid 5-oxo-5,6,7,8-tetrahydro-naphthalen-2-yl ester and 1-methyl-2-cyanopyrrole according to the coupling procedure as described in example 1. MS (ES) m/z 251.2; HRMS: calcd for C16H14N2O+H+, 251.11789; found (ESI, [M+H]+), 251.1186.

Sources & evidence

ORD record
ord-5a618873f04945ba9772ddd8c9c6a6ac
Source dataset
uspto-grants-2008_01
Patent number
US07319152B2

Reaction notes

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