5-Chlorothiophene-2-boronic acid → HCID 24987021, compound

HRID 2251662Notes

Reaction equation

HRID 2251662 reaction equation
[CH3:1][C:2]1([CH3:20])[C:10]2[C:5](=[CH:6][CH:7]=[C:8](OS(C(F)(F)F)(=O)=O)[CH:9]=2)[C:4](=[O:19])[CH2:3]1.[Cl:21][C:22]1[S:26][C:25](B(O)O)=[CH:24][CH:23]=1>>[Cl:21][C:22]1[S:26][C:25]([C:8]2[CH:9]=[C:10]3[C:5](=[CH:6][CH:7]=2)[C:4](=[O:19])[CH2:3][C:2]3([CH3:1])[CH3:20])=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 27343245-Chlorothiophene-2-boronic acidHCID 57618520Trifluoromethanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester

Product 1

HCID 24987021HCID 24987021, compound

Procedure

The title compound was prepared from trifluoro-methanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester and 5-chlorothien-2-yl boronic acid according to the procedure described in example 21. MS m/z 277; HRMS: calcd for C15H13ClOS+H+, 277.04484; found (ESI, [M+H]+), 277.0444.

Sources & evidence

ORD record
ord-02d379f51e19477d8a751641c45c6bdb
Source dataset
uspto-grants-2008_01
Patent number
US07319152B2

Reaction notes

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