Thiophene-3-boronic acid → HCID 24987020, compound

HRID 2251663Notes

Reaction equation

HRID 2251663 reaction equation
[CH3:1][C:2]1([CH3:20])[C:10]2[C:5](=[CH:6][CH:7]=[C:8](OS(C(F)(F)F)(=O)=O)[CH:9]=2)[C:4](=[O:19])[CH2:3]1.[S:21]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22]1>>[CH3:20][C:2]1([CH3:1])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:23]3[CH:24]=[CH:25][S:21][CH:22]=3)[CH:9]=2)[C:4](=[O:19])[CH2:3]1

Participants

3

Reactant 2

HCID 581760Thiophene-3-boronic acidHCID 57618520Trifluoromethanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester

Product 1

HCID 24987020HCID 24987020, compound

Procedure

The title compound was prepared from trifluoro-methanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester and thien-3-yl boronic acid according to the procedure described in example 21. MS m/z 243; HRMS: calcd for C15H14OS+H+, 243.08381; found (ESI, [M+H]+), 243.084.

Sources & evidence

ORD record
ord-67829104ed094302ab8abbe94deba353
Source dataset
uspto-grants-2008_01
Patent number
US07319152B2

Reaction notes

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