Benzaldehyde → HCID 58880521, compound

Participants

Reaction Steps

4 g of (3,4-bis-hydroxymethylphenyl)methanol (23.8 mmol), 40 ml of toluene, 3.06 g of benzaldehyde (28.5 mmol) and 0.24 g of Montmorillonite KSF (10 mg/mmol) are introduced into a flask equipped with a Dean-Stark. The medium is heated under reflux for 3 hours. After filtration, the toluene is evaporated under vacuum at 30° C. The residue is chromatographed on silica gel (heptane/ethyl acetate=7/3) to give 1.8 g of (7-phenyl)-(5H,9H)-6,8-dioxabenzocyclohepten-2-yl)methanol in the form of a white powder.

Provenance & Evidence