Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251789Generated: November 1, 2026

HCID 59644057, compound → (2R,4R,6R)-2-Hydroxy-2-((R)-2-oxothiazolidin-4-yl)-6-phenethyl-tetrahydro-2H-pyran-4-yl Benzoate

https://huagongshe.com/reaction/2251789

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59644057HCID 59644057—
Reactant(R)-4-((1R,4Z,8Z,13R,15R)-15-methoxy-5-methyl-3-oxo-2,14-dioxa-bicyclo[11.3.1]heptadeca-4,8-dien-15-yl)-3-(4-methoxybenzyl)thiazolidin-2-oneHCID 59644077—
Product(2R,4R,6R)-2-Hydroxy-2-((R)-2-oxothiazolidin-4-yl)-6-phenethyl-tetrahydro-2H-pyran-4-yl BenzoateHCID 24888317—

Reaction Steps

Application of the method shown in Example 46, with the modification that (2R,4R,6R)-2-methoxy-2-((R)-3-(4-methoxybenzyl)-2-oxothiazolidin-4-yl)-6-phenethyl-tetrahydro-2H-pyran-4-yl benzoate is substituted for (R)-4-((1R,4Z,8Z,13R,15R)-15-methoxy-5-methyl-3-oxo-2,14-dioxa-bicyclo[11.3.1]heptadeca4,8-dien-15-yl)-3-(4-methoxybenzyl)thiazolidin-2-one, affords the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07320974B2
Source datasetuspto-grants-2008_01
ORD IDord-b40d8fe24c2e4b6db378298e2bba2719
Source noteuspto-grants-2008_01