HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69034326, compound → HCID 69031997, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69034326 | HCID 69034326 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 69031997 | HCID 69031997 | — |
Reaction Steps
A solution of 2-(4-tert-butyl-phenyl)-7-nitro-2,3-dihydro-isoindol-1-one (110 mg, 0.35 mmol) and EtOAc (50 mL) was hydrogenated over 10% Pd/C (80 mg) at 1 atm and RT. After 2.5 h, the mixture was filtered through Celite® and concentrated in vacuo to afford the desired amine as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320992B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-c272c02b26794403856bc2c3dd1d182e |
| Source note | uspto-grants-2008_01 |