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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251848Generated: November 1, 2026

HCID 69034326, compound → HCID 69031997, compound

https://huagongshe.com/reaction/2251848

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69034326HCID 69034326—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 69031997HCID 69031997—

Reaction Steps

A solution of 2-(4-tert-butyl-phenyl)-7-nitro-2,3-dihydro-isoindol-1-one (110 mg, 0.35 mmol) and EtOAc (50 mL) was hydrogenated over 10% Pd/C (80 mg) at 1 atm and RT. After 2.5 h, the mixture was filtered through Celite® and concentrated in vacuo to afford the desired amine as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07320992B2
Source datasetuspto-grants-2008_01
ORD IDord-c272c02b26794403856bc2c3dd1d182e
Source noteuspto-grants-2008_01