HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → N-[4-(1-phenyl-1,2,4,5-tetrahydrobenzo[d]azepin-3-yl)-butyl]-3-pyridin-3-yl-acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-(3-Pyridinyl)-2-propenoic acid | HCID 101984 | — |
| Reactant | HCID 17940755 | HCID 17940755 | — |
| Product | N-[4-(1-phenyl-1,2,4,5-tetrahydrobenzo[d]azepin-3-yl)-butyl]-3-pyridin-3-yl-acrylamide | HCID 54436656 | — |
Reaction Steps
Batch size: 2.8 g (18.8 mmol) 3-(3-Pyridyl)-acrylic acid, 2.2 ml (25.5 mmol) oxalyl chloride and 5.0 g (17.0 mmol) 4-(1-phenyl-1,2,4,5-tetrahydrobenzo[d]azepin-3-yl)-butylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320993B1 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-74fc246b6aa54ba3ba83c83b4c5ab6f8 |
| Source note | uspto-grants-2008_01 |