N-Iodosuccinimide → HCID 12321880, compound

Participants

Reaction Steps

Treat a solution of 2-phenylimidazo[1,2-a]pyridine (50 mg, 0.257 mmol) in acetonitrile (1.25 mL) with N-iodosuccinimide (NIS) (69 mg, 0.309 mmol) at room temperature for 5 hours. Dilute the mixture with ether (10 mL), wash with a saturated aqueous solution of NaHCO3 (15 mL) and NaHSO3 (40%, 15 mL), dry (Na2SO4) and concentrate in vacuo. A yellow solid is obtained, 80 mg, 97% yield. MS(ES+): m/z=321.0 (M+H)+

Provenance & Evidence