HCID 69212492, compound → HCID 85937142, compound

Participants

Reaction Steps

Dissolve 4-(N-tert-butoxycarbonyl-N-ethyl-amino)-benzyl alcohol (1.24 g, 5.52 mmol) in 50 mL acetonitrile. Add to this solution manganese dioxide and stir the mixture for two days at room temperature. Filter the residue through Celite® and concentrate the solvent to give 632 mg of 4-(N-tert-butoxycarbonyl-N-ethyl-amino) benzaldehyde. Yield 52%. 1H-NMR (CDCl3, 300 MHz): 9.95 (s, 1H); 7.83 (d, J=8.7 Hz, 2H); 7.39 (d, J=8.7 Hz, 2H); 3.74 (q, J=7.0 Hz, 2H); 1.45 (s, 9H); 1.18 (t, J=7.0 Hz, 3H).

Provenance & Evidence