Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 2,4-Dibromo-1-nitrobenzene | HCID 12315646 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 5-Bromo-2-nitroaniline | HCID 5314766 | — |
Reaction Steps
In a sealed reaction tube, add cautiously 6 mL of an aqueous solution of ammonia (32%) to a solution of 2,4-dibromonitrobenzene (1,6 g) in 2 mL of DMSO. Stir for 18 hours at 100° C. and cool to room temperature. Pour the heterogeneous mixture into water and filter the title compound (1.1 g, 92%) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07320995B2 |
|---|
| Source dataset | uspto-grants-2008_01 |
|---|
| ORD ID | ord-f67818b6998f4bb895edd2710c6aeff0 |
|---|
| Source note | uspto-grants-2008_01 |
|---|
