Aluminium lithium hydride → HCID 59644267, compound

Participants

Reaction Steps

To a solution of Example 209 (0.15 g, 0.32 mmol) in THF (5.0 ml) was added LAH (1.0 M in THF, 0.66 ml, 0.66 mmol) at 0° C. The mixture was stirred at room temperature overnight before it was quenched with Na2SO4.10H2O (pellets) until no further bubbles was observed. The mixture was diluted with ethyl acetate and the solids filtered. The filterate was washed with water (50 ml), brine (50 ml), dried over MgSO4 and concentrated on a rotovap to give the desired alcohol as a yellow solid (0.04 g, 27%).

Provenance & Evidence