HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyridine → 2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid pyridin-3-ylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | 2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chloride | HCID 4962506 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid pyridin-3-ylamide | HCID 69052510 | 38% |
Reaction Steps
A solution of 5-chlorosufonyl-2-oxindole (3 g) and 3-aminopyridine (1.46 g) in pyridine (15 mL) was stirred at room temperature overnight at which time a brown solid was present. The solid was filtered, washed with ethanol and dried under vacuum to yield 1.4 g (38%) of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid pyridin-3-ylamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320996B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-642753a73f5b4b2a886409a3e23659f7 |
| Source note | uspto-grants-2008_01 |