Oxindole → HCID 54260743, compound
Reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[O:10].[CH:11]([C:13]1[NH:17][C:16]([C:18]([OH:20])=[O:19])=[CH:15][C:14]=1[CH3:21])=O>>[CH3:21][C:14]1[CH:15]=[C:16]([C:18]([OH:20])=[O:19])[NH:17][C:13]=1[CH:11]=[C:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[NH:1][C:2]1=[O:10]Participants
3
Procedure
Oxindole (133 mg, 1 mmol) was condensed with 5-formyl-4-methyl-1H-pyrrole-2-carboxylic acid (153 mg) using method D to give 268 mg (100%) of the title compound as an orange-red solid.
Sources & evidence
- ORD record
- ord-8492523c62c04afeb8e60d5cbf8e2101
- Source dataset
- uspto-grants-2008_01
- Patent number
- US07320996B2
Reaction notes
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