HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methyloxindole → 4-Methyl-5-(1-methyl-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methyloxindole | HCID 6096 | — |
| Reactant | 5-formyl-4-methyl-1H-pyrrole-2-carboxylic Acid | HCID 9898884 | — |
| Product | 4-Methyl-5-(1-methyl-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic acid | HCID 67281554 | 88.6% |
Reaction Steps
1-Methyl-1,3-dihydroindol-2-one (147 mg, 1 mmol) was condensed with 5-formyl-4-methyl-1H-pyrrole-2-carboxylic acid (153 mg) using method D to give 250 mg (86%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320996B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-d6fa909fa58a47849734130da96cdea1 |
| Source note | uspto-grants-2008_01 |