HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-oxindole → 5-(5-Bromo-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-2-methyl-4-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-oxindole | HCID 611193 | — |
| Reactant | 5-formyl-2-methyl-4-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 20604779 | — |
| Product | 5-(5-Bromo-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-2-methyl-4-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 67281551 | 60% |
Reaction Steps
5-Bromo-1,3-dihydroindol-2-one (60 mg, 0.29 mmol) was condensed with 5-formyl-2-methyl-4-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester (75 mg) to give 78 mg (60%) of the title compound as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320996B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-d354f330081b4a2a98baf4534fe1556f |
| Source note | uspto-grants-2008_01 |