HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-oxindole → 5-(5-Bromo-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-dimethylaminoethyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-oxindole | HCID 611193 | — |
| Reactant | HCID 54380946 | HCID 54380946 | — |
| Product | 5-(5-Bromo-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-dimethylaminoethyl)amide | HCID 67281698 | 86.9% |
Reaction Steps
5-Bromo-1,3-dihydroindol-2-one (0.17 g, 0.8 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-dimethylaminoethyl)amide (0.2 g, prepared by method C) using method B to give 0.3 g (83%) of the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320996B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-6489573a7e6048d09c6f4a91d1c8d3bf |
| Source note | uspto-grants-2008_01 |