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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2252159Generated: October 30, 2026

5-Chlorooxindole → 5-(5-Chloro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-dimethylaminoethyl)amide

https://huagongshe.com/reaction/2252159

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-ChlorooxindoleHCID 152801—
ReactantHCID 54380946HCID 54380946—
Product5-(5-Chloro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-dimethylaminoethyl)amideHCID 6728088594.8%

Reaction Steps

5-Chloro-1,3-dihydroindol-2-one (0.1 g, 0.6 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-dimethylaminoethyl)amide (0.15 g) to give 0.22 g (90%) of the title compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07320996B2
Source datasetuspto-grants-2008_01
ORD IDord-2c99d46493734a00a58b1f3627470675
Source noteuspto-grants-2008_01