HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-formyl-2,4-dimethyl-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrole-3-carboxamide → 5-[6-(3-Isopropylphenyl)-2-oxo-1,2-dihydroindol 3-ylidenemethyl]-2,4-dimethyl-1H-pyrrole 3-carboxylic Acid (2-pyrrolidin-1-ylethyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-formyl-2,4-dimethyl-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrole-3-carboxamide | HCID 20761729 | — |
| Reactant | 6-(3-Isopropylphenyl)indolin-2-one | HCID 21915573 | — |
| Product | 5-[6-(3-Isopropylphenyl)-2-oxo-1,2-dihydroindol 3-ylidenemethyl]-2,4-dimethyl-1H-pyrrole 3-carboxylic Acid (2-pyrrolidin-1-ylethyl)amide | HCID 67281290 | 63% |
Reaction Steps
6-(3-Isopropylphenyl)-1,3-dihydroindol-2-one (48 mg, 0.19 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-pyrrolidin-1-ylethyl)amide (50 mg) to give 59 mg (63%) of the title compound as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320996B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-205f7a8724af411f8e70a6465e3a8a39 |
| Source note | uspto-grants-2008_01 |